Clínica Médica

Como os médicos administram os conflitos com familiares de pacientes críticos durante conversas sobre decisões de fim de vida nos cuidados intensivos neonatal, pediátrico e adulto.

5 Jul, 2022 | 11:28h

How doctors manage conflicts with families of critically ill patients during conversations about end-of-life decisions in neonatal, pediatric, and adult intensive care – Intensive Care Medicine

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Revisão | Redução e aumento dos níveis de urato sérico: efeitos off-label de medicações comumente usadas.

5 Jul, 2022 | 11:26h

Lowering and Raising Serum Urate Levels: Off-Label Effects of Commonly Used Medications – Mayo Clinic Proceedings

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Diretrizes 2022 para o tratamento e a profilaxia do tromboembolismo venoso em pacientes com câncer, incluindo aqueles com COVID-19.

4 Jul, 2022 | 12:24h

2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19 – The Lancet Oncology

Conteúdos relacionados:

Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy – Cochrane Library

American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer – Blood Advances

Cancer-Associated Venous Thromboembolic Disease, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Venous and Arterial Thromboembolism in Patients With Cancer: JACC: CardioOncology State-of-the-Art Review

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Dois novos estudos mostram que a enoxaparina não tem benefício na tromboprofilaxia primária de pacientes ambulatoriais sintomáticos com COVID-19.

4 Jul, 2022 | 12:23h

Estudo 1: Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial – The Lancet Haematology

Estudo 2: Thromboprophylactic low-molecular-weight heparin versus standard of care in unvaccinated, at-risk outpatients with COVID-19 (ETHIC): an open-label, multicentre, randomised, controlled, phase 3b trial – The Lancet Haematology

Comentários:

Antithrombotic prophylaxis for symptomatic outpatients with COVID-19: less is consistently more – The Lancet Haematology

Antithrombotic Prophylaxis No Help in Outpatients With COVID — Two trials show no differences between patients who received enoxaparin vs standard of care – MedPage Today (necessário cadastro gratuito)

 

Comentário no Twitter (fio – clique para saber mais)

Early in the pandemic we wondered whether antithrombotic therapy in outpatients with #COVID19 would prevent #thrombosis ❓

Several trials were started globally and the ACTIV-4B trial was previously reported⬇️ https://t.co/Q15WcZwDIA

Now, we publish the OVID and ETHIC trials🧵

— The Lancet Haematology (@TheLancetHaem) June 30, 2022

 

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Acurácia do teste rápido de antígeno vs. RT-PCR para infecção por SARS-CoV-2 em atletas universitários durante a prevalência da variante Ômicron.

4 Jul, 2022 | 12:18h

Accuracy of Rapid Antigen vs Reverse Transcriptase–Polymerase Chain Reaction Testing for SARS-CoV-2 Infection in College Athletes During Prevalence of the Omicron Variant – JAMA Network Open

 

Comentário no Twitter

In this case series of college athletes returning to campus during Omicron, rapid antigen tests were 63% sensitive, >99% specific for #COVID19, similar to previous strains and less well in detecting asymptomatic #SARSCoV2. @helixcardinal @stanford_ortho https://t.co/SBPr6NQ9Na

— JAMA Network Open (@JAMANetworkOpen) June 15, 2022

 

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Consenso para definição, classificação, diagnóstico e tratamento da urticária.

4 Jul, 2022 | 12:10h

Taiwanese dermatological association consensus for the definition, classification, diagnosis, and management of urticaria: A 2021 update – Journal of the Formosan Medical Association

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Análise agrupada de estudos clínicos placebo-controlados | Segurança da empagliflozina em pacientes com diabetes tipo 2 e doença renal crônica.

4 Jul, 2022 | 11:38h

Safety of Empagliflozin in Patients With Type 2 Diabetes and Chronic Kidney Disease: Pooled Analysis of Placebo-Controlled Clinical Trials – Diabetes Care

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M-A | Analgesia com opioide vs. sem opioide após alta cirúrgica.

22 Jun, 2022 | 21:43h

Opioid versus opioid-free analgesia after surgical discharge: a systematic review and meta-analysis of randomised trials – The Lancet (link para o resumo – $ para o texto completo)

Comunicado de imprensa: Taking opioids at home after surgery: More harms than benefits – McGill University Health Center

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Estudo randomizado | Metilprednisolona em baixa dose não melhora os desfechos em pacientes críticos com pneumonia grave adquirida na comunidade.

22 Jun, 2022 | 21:40h

Low-dose methylprednisolone treatment in critically ill patients with severe community-acquired pneumonia – Intensive Care Medicine

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Quão comum é a COVID longa? Razões para os estudos darem respostas diferentes.

22 Jun, 2022 | 21:38h

How common is long COVID? Why studies give different answers – Nature

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