Clínica Médica

Análise provisória | Sabizabulina oral para adultos de alto risco internados com Covid-19.

11 Jul, 2022 | 13:59h

Oral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19: Interim Analysis – NEJM Evidence

 

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Estudo randomizado | Plasma convalescente neutralizante de COVID-19 não traz benefícios a adultos internados com a doença.

11 Jul, 2022 | 13:58h

Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized with COVID-19: A Blinded Randomized Placebo-Controlled Trial – CHEST

Comentário: Study shows convalescent plasma doesn’t benefit severely ill patients hospitalized with COVID-19 – Vanderbilt University Medical Center

 

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M-A | Associações entre uso de diuréticos tiazídicos e câncer de pele.

11 Jul, 2022 | 13:55h

Associations of thiazide use with skin cancers: a systematic review and meta-analysis – BMC Medicine

Conteúdos relacionados:

Association between antihypertensive medications and risk of skin cancer in people older than 65 years: a population-based study – Canadian Medical Association Journal

Association of Hydrochlorothiazide Use and Risk of Malignant Melanoma – JAMA Internal Medicine

Hydrochlorothiazide use and risk of nonmelanoma skin cancer: A nationwide case-control study from Denmark – Journal of the American Academy of Dermatology

 

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Diretrizes de consenso sobre diagnóstico e tratamento de apneia obstrutiva do sono em pacientes com doença cardiovascular.

11 Jul, 2022 | 13:51h

Asian Pacific Society of Cardiology Consensus Statements on the Diagnosis and Management of Obstructive Sleep Apnoea in Patients with Cardiovascular Disease – European Cardiovascular Review

 

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Estudo randomizado | Neuromodulação sacral para disfunção neurogênica do trato urinário inferior.

11 Jul, 2022 | 13:49h

Sacral Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction – NEJM Evidence

 

Comentário no Twitter

Pts with neurogenic lower urinary tract dysfunction had sacral neuromodulators implanted and optimized. They were then randomized to have the device either remain ON or switched OFF for 2 months. The success rate was 76% in the ON group vs 42% in the OFF. https://t.co/dhteW70jXp pic.twitter.com/1c0w8HOMJm

— NEJM Evidence (@NEJMEvidence) July 7, 2022

 

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Estudo randomizado | Efeito da eletroacupuntura sobra a insônia em pacientes com depressão.

11 Jul, 2022 | 13:48h

Effect of Electroacupuncture on Insomnia in Patients With Depression: A Randomized Clinical Trial – JAMA Network Open

Comentário convidado: Effects of Electroacupuncture for Depression-Related Insomnia – JAMA Network Open

 

Comentário no Twitter

This randomized clinical trial found that an 8-weeek electroacupuncture with standard care improved sleep quality for patients with insomnia and depression, compared with sham acupuncture and/or standard care. https://t.co/nacnxEI4Ik

— JAMA Network Open (@JAMANetworkOpen) July 7, 2022

 

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Revisão sistemática e metanálise dose-resposta de estudos de coorte prospectiva | Ingestão de ovos e colesterol na dieta e risco de mortalidade por todas as causas, cardiovascular e por câncer.

11 Jul, 2022 | 13:33h

Egg and Dietary Cholesterol Intake and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies – Frontiers in Nutrition

 

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Estudo de caso controle e teste negativo | Efetividade da 4ª dose de vacina de mRNA contra Covid-19 causada pela variante Ômicron entre residentes de instituições de longa permanência em Ontário, Canadá.

8 Jul, 2022 | 11:30h

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

 

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Revisão | Doença falciforme.

8 Jul, 2022 | 11:28h

Sickle Cell Disease: A Review – JAMA (gratuito por tempo limitado)

Revisão clínica em áudio: Sickle Cell Disease – JAMA

 

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Estudo de coorte retrospectiva | Viés racial e reprodutibilidade da oximetria de pulso entre pacientes internados clínicos e cirúrgicos.

8 Jul, 2022 | 11:24h

Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients in general care in the Veterans Health Administration 2013-19: multicenter, retrospective cohort study – The BMJ

Comunicado de imprensa: Pulse oximeters missed low oxygen levels in more Black veterans than white veterans – University of Michigan

Conteúdos relacionados:

Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 – JAMA Internal Medicine

Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

 

Comentário no Twitter

New research found that for individuals in general (medical and surgical) care in hospital, occult hypoxemia was more common for black patients than for white patients https://t.co/DrNlaIE7ho

— The BMJ (@bmj_latest) July 6, 2022

 

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