Clínica Médica

Estudo randomizado | Leflunomida vs. azatioprina como terapia de manutenção da nefrite lúpica.

13 Jul, 2022 | 12:23h

Leflunomide versus azathioprine for maintenance therapy of lupus nephritis: a prospective, multicentre, randomised trial and long-term follow-up – Annals of Rheumatic Diseases

 

Comentário no Twitter

🆕🔥Leflunomide versus azathioprine for maintenance therapy of lupus nephritis
🫘LEF=AZR in maintenance for SLE-LN
🫘Induction with NIH-CYC
🫘Chinese seem to love Lefno
🫘Generalisability difficult
Would have loved an MMF vs LEF#Rheumtwitter #Nephtwitterhttps://t.co/N2gTYISibM pic.twitter.com/nlP2LkSu8c

— EnvisionRheumat (@ERheumat) July 5, 2022

Sob licença de http://creativecommons.org/licenses/by-nc/4.0/

 

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M-A | Acurácia do diagnóstico baseado em teste rápido de antígeno para SARS-CoV-2.

13 Jul, 2022 | 12:21h

Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: An updated systematic review and meta-analysis with meta-regression analyzing influencing factors – PLOS Medicine

Conteúdos relacionados:

Interpreting a lateral flow SARS-CoV-2 antigen test – The BMJ

Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library

 

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Diretriz científica NLA sobre intolerância a estatina: uma nova definição e considerações principais para redução do risco de doença cardiovascular aterosclerótica no paciente intolerante à estatina.

13 Jul, 2022 | 12:19h

NLA scientific statement on statin intolerance: a new definition and key considerations for ASCVD risk reduction in the statin intolerant patient – Journal of Clinical Lipidology

Comentário: National Lipid Association Scientific Statement on Statin Intolerance – American College of Cardiology

 

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Navegando em um mundo complicado | Comentário sobra as novas diretrizes de dor torácica do AHA/ACC.

13 Jul, 2022 | 12:16h

Navigating a Complicated World: The American Heart Association/American College of Cardiology/American College of Chest Physicians/Society of Academic Emergency Medicine/Society of Cardiovascular Computed Tomography/Society of Cardiovascular Magnetic Resonance Chest Pain Guidelines – CHEST

Diretriz original: 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

Comunicado de imprensa: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released

Eixo da diretriz: Guideline for the Evaluation and Diagnosis of Chest Pain

Pontos principais: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology

Comentário: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD

 

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Estudo de coorte | Crescimento de aneurisma, sobrevida e qualidade de vida em aneurismas aórticos torácicos não tratados.

13 Jul, 2022 | 12:07h

Aneurysm growth, survival, and quality of life in untreated thoracic aortic aneurysms: the effective treatments for thoracic aortic aneurysms study – European Heart Journal

Comentário: Growth, Survival, Quality of Life in Untreated Thoracic Aortic Aneurysms – American College of Cardiology

 

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M-A | Fatores correlacionados a função física 1 ano após artroplastia total de joelho em pacientes com osteoartrite de joelho.

13 Jul, 2022 | 12:06h

Factors Correlated With Physical Function 1 Year After Total Knee Arthroplasty in Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis – JAMA Network Open

 

Comentário no Twitter

This meta-analysis of 20 prospective cohort studies (11,317 patients) found associations between presurgical BMI, physical function, and osteoarthritis severity and physical function after total knee arthroplasty (TKA). https://t.co/tQf7HytTEW

— JAMA Network Open (@JAMANetworkOpen) July 11, 2022

 

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M-A de estudos randomizados | Eficácia e segurança da leflunomida combinada com corticosteroides para o tratamento da nefropatia por IgA.

13 Jul, 2022 | 11:47h

Efficacy and safety of leflunomide combined with corticosteroids for the treatment of IgA nephropathy: a Meta-analysis of randomized controlled trials – Renal Failure

 

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Diretriz ESAIC/ESRA | Anestesia regional em pacientes em uso de medicamentos antitrombóticos.

12 Jul, 2022 | 11:57h

Regional anaesthesia in patients on antithrombotic drugs: Joint ESAIC/ESRA guidelines – European Journal of Anaesthesia

 

Comentário no Twitter

Just saw this from 2/22-More reasonable recommendations than ASRA for timeframe to stop Xa's before regional anesthesia (not 96hrs) but including drug levels in some recs
Regional anaesthesia in pts on antithrombotic drugs: Joint ESAIC/ESRA guidelines https://t.co/PrF72HFWzG

— Steven Cohn, MD (@preopconsult) July 10, 2022

 

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European Medicines Agency recomenda reforço de vacina contra COVID em pessoas com mais de 60 anos.

12 Jul, 2022 | 11:54h

European Medicines Agency Recommends Second COVID Booster for People Over 60 – as WHO Ponders Guidance – Health Policy Watch

 

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M-A | Pouco benefício da viscossuplementação na osteoartrose de joelho.

12 Jul, 2022 | 11:52h

Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis – The BMJ

Comunicado de imprensa: Scant evidence to recommend use of hyaluronic acid injections for knee osteoarthritis – BMJ Newsroom

Comentário: Common injections don’t help knee osteoarthritis more than placebo, large data review finds – STAT

 

Comentário no Twitter

New research finds that injections of hyaluronic acid to treat knee osteoarthritis make almost no difference to pain and might raise risk of adverse events https://t.co/G80BHoOgl3

— The BMJ (@bmj_latest) July 7, 2022

 

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