Clínica Médica

Estudo randomizado | Acetazolamida previne os efeitos adversos da altitude tanto em adultos saudáveis quanto em portadores de DPOC.

28 Jan, 2022 | 15:28h

Acetazolamide to Prevent Adverse Altitude Effects in COPD and Healthy Adults – NEJM Evidence

Conteúdo relacionado: A Randomized Controlled Trial of the Lowest Effective Dose of Acetazolamide for Acute Mountain Sickness Prevention

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Um sistema de inteligência artificial pode ajudar a prever infarto miocárdico por meio de escaneamento da retina e informações pessoais mínimas.

28 Jan, 2022 | 15:21h

Comunicado de imprensa: Using the eye as a window into heart disease – University of Leeds

Estudo original: Predicting myocardial infarction through retinal scans and minimal personal information – Nature Machine Intelligence (link para o resumo – $ para o texto completo)

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Um estudo de registro com 1.581 casos de Stenotrophomonas maltophilia sanguínea e/ou infecções de trato respiratório inferior sugere que levofloxacino é uma alternativa razoável à terapia padrão com trimetoprima-sulfametoxazol.

28 Jan, 2022 | 15:19h

Trimethoprim-Sulfamethoxazole versus Levofloxacin for Stenotrophomonas maltophilia Infections: A Retrospective Comparative Effectiveness Study of Electronic Health Records from 154 U.S. Hospitals – Open Forum Infectious Diseases

 

Comentário no Twitter

A new study in OFID suggests that mortality outcomes are similar comparing levofloxacin and TMP/SMX treatment of S. maltophilia lower respiratory tract and bloodstream infections.

📄:https://t.co/80QDy3DTU9 #IDSAJournals @PaulSaxMD @DrJLi @Keith_S_Kaye @SameerKadri12 pic.twitter.com/TNxQpfT97n

— IDSA (@IDSAInfo) January 23, 2022

 

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Febre de origem indeterminada e incidência de câncer: um estudo de coorte de base populacional usando registros nacionais da Dinamarca mostrou que o risco de câncer em 1 ano foi de 1,2%.

28 Jan, 2022 | 15:18h

Fever of unknown origin and incidence of cancer – Clinical Infectious Diseases (link para o resumo – $ para o texto completo)

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Revisão sistemática | Ultrafiltração para insuficiência cardíaca aguda.

28 Jan, 2022 | 15:16h

Ultrafiltration for acute heart failure – Cochrane Library

Comentário: Fluid removal therapy in acute heart failure – Cochrane Library

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Revisão sistemática | Combinações orais de anti-histamínico–descongestionante–analgésico para resfriado comum.

28 Jan, 2022 | 15:15h

Oral antihistamine‐decongestant‐analgesic combinations for the common cold – Cochrane Library

Comentário: Oral antihistamine-decongestant-analgesic combinations for the common cold – Cochrane Library

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Suplemento | Síndrome do intestino irritável e condições relacionadas.

28 Jan, 2022 | 15:09h

Página principal: IBS and Related Conditions – Alimentary Pharmacology and Therapeutics

Review article: epidemiology of IBS and other bowel disorders of gut–brain interaction (DGBI)

Review article: Physical and psychological comorbidities associated with irritable bowel syndrome

Review article: irritable bowel syndrome: natural history, bowel habit stability and overlap with other gastrointestinal disorders

Review article: Diagnosis and investigation of irritable bowel syndrome

Review article: the patients’ experience with irritable bowel syndrome and their search for education and support

Review article: current and future treatment approaches for IBS with constipation

Review Article: Current and future treatment approaches for IBS with diarrhoea (IBS-D) and IBS mixed pattern (IBS-M)

Review article: current and future treatment approaches for pain in IBS

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Estudo randomizado | CPAP melhora os desfechos em pacientes com insuficiência respiratória hipoxêmica aguda decorrente de COVID-19, mas cateter nasal de alto fluxo não é melhor que a oxigenoterapia convencional.

25 Jan, 2022 | 15:10h

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial – JAMA

Editorial: Defining Optimal Respiratory Support for Patients With COVID-19 – JAMA

 

Comentário no Twitter

RCT of patients with acute hypoxemic respiratory failure due to #COVID19 found an initial strategy of CPAP, compared with conventional oxygen therapy, significantly reduced the composite outcome of tracheal intubation or mortality within 30 days. https://t.co/fznFigiFmu pic.twitter.com/b7mHssbfkp

— JAMA (@JAMA_current) January 24, 2022

 

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Breve revisão ACP | Risco de reinfecção após contágio pelo SARS-CoV-2.

25 Jan, 2022 | 15:07h

Risk for Reinfection After SARS-CoV-2: A Living, Rapid Review for American College of Physicians Practice Points on the Role of the Antibody Response in Conferring Immunity Following SARS-CoV-2 Infection – Annals of Internal Medicine

 

Comentário no Twitter

Risk for Reinfection After #SARSCoV2: previous infection reduced risk for reinfection by 87% (95% CI, 84% to 90%). Protection remained above 80% for at least 7 months, but no study followed patients after the emergence of the Delta or #Omicron variant. https://t.co/eruEf1w8Vo

— Prof. Nick Talley (@Prof_NickTalley) January 25, 2022

 

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OMS deixa de se opor aos reforços de vacina – recomenda a terceira dose da Pfizer para adultos e 2 doses de vacinas para crianças a partir de 5 anos de idade.

25 Jan, 2022 | 15:06h

WHO Drops Opposition to Boosters – Recommends Third Pfizer Jab for Adults & Two Vaccines for Children Ages 5 & Up – Health Policy Watch

Conteúdos relacionados:

WHO updated roadmap for prioritizing uses of COVID-19 vaccines.

WHO advisers weigh in on COVID-19 boosters, Pfizer vaccine in younger kids.

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