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Clínica Médica

Prescrição de nirmatrelvir-ritonavir para Covid-19: como reconhecer e administrar as interações medicamentosas.

2 Mar, 2022 | 11:40h

Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions – Annals of Internal Medicine

Conteúdos relacionados:

Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.

Pfizer antiviral pills may be risky with other medications – NBC News

The New COVID-19 Pill, Paxlovid, Interacts with Many Medications: Cardiac Patients Take Note – The Skeptical Cardiologist

Diretriz NICE | Bem-estar mental no trabalho.

2 Mar, 2022 | 11:37h

Mental wellbeing at work – National Institute for Health and Care Excellence

Revisão | Diagnóstico e tratamento da sarcoidose pulmonar.

2 Mar, 2022 | 11:34h

Diagnosis and Treatment of Pulmonary Sarcoidosis: A Review – JAMA (gratuito por tempo limitado)

Conteúdos relacionados:

ERS clinical practice guidelines on treatment of sarcoidosis.

ATS Guideline: Diagnosis and Detection of Sarcoidosis

WASOG statement on the diagnosis and management of sarcoidosis-associated pulmonary hypertension.

Sarcoidosis: A clinical overview from symptoms to diagnosis.

Podcast: Sarcoidosis

Clinical Manifestations, Diagnosis, and Treatment of Sarcoidosis

Revisão sistemática | Índices de diarreia pós-colecistectomia e fatores preditivos.

2 Mar, 2022 | 11:33h

Postcholecystectomy diarrhoea rate and predictive factors: a systematic review of the literature – BMJ Open

M-A | Sobrevida de pacientes com insuficiência renal que estavam em lista de espera e receberam transplante vs. os que permaneceram na lista de espera.

2 Mar, 2022 | 11:31h

Survival for waitlisted kidney failure patients receiving transplantation versus remaining on waiting list: systematic review and meta-analysis – The BMJ

Diretriz atualizada da Joint British Diabetes Society for Inpatient Care | Tratamento da cetoacidose diabética em adultos.

1 Mar, 2022 | 15:41h

The management of diabetic ketoacidosis in adults—An updated guideline from the Joint British Diabetes Society for Inpatient Care

Diretriz atualizada | Momento da cirurgia eletiva e avaliação de risco após infecção por SARS-CoV-2 – “Mantemos a orientação de que os pacientes devem evitar cirurgias eletivas dentro de 7 semanas da infecção, a menos que os benefícios superem o risco de aguardar por tal período.”

1 Mar, 2022 | 15:38h

Timing of elective surgery and risk assessment after SARS-CoV-2 infection: an update – Anaesthesia

Conteúdos relacionados:

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

Revisão sistemática sobre uso inapropriado de práticas clínicas no Canadá identificou 144 práticas subutilizadas, 109 práticas usadas em excesso e 25 práticas que atendiam a ambos os critérios.

1 Mar, 2022 | 15:32h

Inappropriate use of clinical practices in Canada: a systematic review – Canadian Medical Association Journal

Comentários: What problems in health care quality should we target as the world burns around us? – Canadian Medical Association Journal

Comunicado de imprensa: Inappropriate use of 228 clinical practices in Canada – Canadian Medical Association Journal

Estudo randomizado | Melatonina profilática não reduz a incidência de delirium em pacientes em UTI.

1 Mar, 2022 | 15:27h

Prophylactic melatonin for delirium in intensive care (Pro-MEDIC): a randomized controlled trial – Intensive Care Medicine (link para o resumo – $ para o texto completo)

 

Comentários no Twitter

 

Revisão | Nova geração de tratamentos psicológicos na dor crônica.

1 Mar, 2022 | 15:25h

New generation psychological treatments in chronic pain – The BMJ (gratuito por tempo limitado)

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