Acesso livre
Acesso livre

Cardiologia

Estudo randomizado | Em pacientes estáveis submetidos a intervenção coronariana percutânea (ICP) para infarto agudo do miocárdio, o de-escalonamento de aspirina+ticagrelor para aspirina+clopidogrel depois de 1 mês reduziu eventos hemorrágicos sem aumentar o risco cardiovascular.

13 Out, 2021 | 12:39h

Unguided de-escalation from ticagrelor to clopidogrel in stabilised patients with acute myocardial infarction undergoing percutaneous coronary intervention (TALOS-AMI): an investigator-initiated, open-label, multicentre, non-inferiority, randomised trial – The Lancet (link para o resumo – $ para o texto completo)

Comentário: Adopting a clopidogrel-based DAPT strategy after PCI boosts outcomes for heart attack patients – Cardiovascular Business

 

É muito baixo o risco de inflamação cardíaca após vacina da Pfizer contra COVID.

12 Out, 2021 | 11:15h

Heart-inflammation risk from Pfizer COVID vaccine is very low – Nature

Estudos originais:

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Estudo sugere que um intervalo de 30 segundos entre aferições automatizadas de pressão arterial em consultório é tão acurado e confiável quanto um intervalo de 60 segundos.

8 Out, 2021 | 12:12h

Impact of 30- Versus 60-Second Time Intervals Between Automated Office Blood Pressure Measurements on Measured Blood Pressure – Hypertension (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

 

Amplo estudo de coorte com mais de 2.5 milhões de indivíduos mostrou que a incidência de miocardite após a vacina da Pfizer foi de 2,13 casos por 100.000 pessoas.

8 Out, 2021 | 12:02h

Myocarditis after Covid-19 Vaccination in a Large Health Care Organization – New England Journal of Medicine

Comentário: Studies Highlight Rarity of Myocarditis With mRNA COVID-19 Vaccines – TCTMD

Estudo relacionado: Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel – New England Journal of Medicine

 

Comentários no Twitter

 

Estudo com mais de 5,1 milhões de indivíduos vacinados mostrou que a incidência de miocardite após receberem a vacina da Pfizer foi baixa e mais comum após a segunda dose em homens jovens.

8 Out, 2021 | 12:00h

Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel – New England Journal of Medicine

Comentário: Studies Highlight Rarity of Myocarditis With mRNA COVID-19 Vaccines – TCTMD

Estudo relacionado: Myocarditis after Covid-19 Vaccination in a Large Health Care Organization – New England Journal of Medicine

 

Comentários no Twitter

 

Suécia e Dinamarca pausam o uso da vacina da Moderna contra COVID-19 em grupos jovens.

8 Out, 2021 | 11:57h

Sweden, Denmark pause Moderna COVID-19 vaccine for younger age groups – Reuters

Extensão variada da disjunção anular mitral entre casos com diferentes fenótipos de prolapso de valva mitral.

8 Out, 2021 | 11:32h

Varied Extent of Mitral Annular Disjunction Among Cases With Different Phenotypes of Mitral Valve Prolapse – JACC: Case Reports

 

Comentário no Twitter

 

Estudo de coorte | Adicionar um novo anti-hipertensivo a regimes já existentes está associado a maiores reduções na pressão arterial do que o aumento da dose do medicamento inicial.

8 Out, 2021 | 11:14h

Adding a New Medication Versus Maximizing Dose to Intensify Hypertension Treatment in Older Adults: A Prospective Observational Study – Annals of Internal Medicine

Comunicado de imprensa: When blood pressure needs more control, what’s better: An additional drug or more of the same? – Michigan Medicine

Comentário: Adding an antihypertensive to existing regimens associated with greater BP reduction than maximizing dose, with some caveats in adherence – ACP Internist

Conteúdo relacionado: #ESCCongress – RCT: Initial hypertension treatment with a single pill with 4 drugs at quarter doses (irbesartan 37.5 mg, amlodipine 1.25 mg, indapamide 0.625 mg, and bisoprolol 2.5 mg) achieved better BP lowering vs. standard monotherapy (irbesartan 150 mg).

 

Comentário no Twitter (fio – clique para saber mais)

 

No fim das contas, o sal faz bem? Evidências dizem que não.

8 Out, 2021 | 11:00h

Is salt good for you after all? The evidence says no – The Conversation

Conteúdos relacionados:

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

Systematic Review: Altered dietary salt intake for people with chronic kidney disease.

New WHO benchmarks help countries reduce salt intake and save lives.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

Revisão | Inibição da agregação plaquetária após colocação de stent coronariano em pacientes em uso de anticoagulação oral.

8 Out, 2021 | 10:55h

Inhibition of Platelet Aggregation After Coronary Stenting in Patients Receiving Oral Anticoagulation – Deutsches Ärzteblatt International

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