Alergia e Imunologia

Diretriz | Plasmaférese e dosagem de glicocorticoides para pacientes com vasculite associada a ANCA.

28 Fev, 2022 | 13:35h

Plasma exchange and glucocorticoid dosing for patients with ANCA-associated vasculitis: a clinical practice guideline – The BMJ

Ver também: The effects of plasma exchange in patients with ANCA-associated vasculitis: an updated systematic review and meta-analysis – The BMJ

Comentário no Twitter

New rapid recommendation makes a weak recommendation against plasma exchange in patients with low risk of end stage kidney disease, and a weak recommendation in favour of plasma exchange in patients with moderate-high risk of ESKD https://t.co/PeEjSuRIxI #BMJInfographic pic.twitter.com/YR55t6XYhS

— The BMJ (@bmj_latest) February 25, 2022

[Preprint] Quarta dose da vacina contra COVID fornece somente um leve reforço contra a infecção pela variante Ômicron.

24 Fev, 2022 | 15:50h

Fourth dose of COVID vaccine offers only slight boost against Omicron infection – Nature

Estudo original: 4th Dose COVID mRNA Vaccines’ Immunogenicity & Efficacy Against Omicron VOC – medRxiv

Dois amplos estudos de base populacional mostram um risco ligeiramente aumentado de eventos trombóticos após vacinação contra COVID-19 com a vacina da AstraZeneca.

24 Fev, 2022 | 15:47h

Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England – PLOS Medicine

Ver também: First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and Wales – PLOS Medicine

Comentários:

Two studies find only small elevated risk of blood clots following AstraZeneca COVID-19 vaccination – PLOS

Two Large Studies Affirm Rare Thrombosis Risk With ChAdOx1 COVID-19 Vax – TCTMD

Estudo randomizado | Descontinuação do metotrexato por 2 semanas em pacientes com artrite reumatoide imunizados com vacina de SARS-CoV-2 inativado.

24 Fev, 2022 | 15:44h

Two-week methotrexate discontinuation in patients with rheumatoid arthritis vaccinated with inactivated SARS-CoV-2 vaccine: a randomised clinical trial – Annals of Rheumatic Diseases

Comentário: Suspend Methotrexate for RA Patients Getting COVID Vax?— It’s not a simple choice, Brazilian study suggests (necessário cadastro gratuito)

Tratamento clínico do prurido associado a doença renal crônica: atuais opções de tratamento e abordagens futuras.

24 Fev, 2022 | 13:32h

Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches – Clinical Kidney Journal

Revisão | Prurido na gestação.

24 Fev, 2022 | 13:31h

Pruritus in Pregnancy – American Journal of Clinical Dermatology

Opinião do Dr. Eric Topol | Por que uma única dose de vacina após infecção por Covid-19 deveria ser suficiente para se considerar uma vacinação completa.

22 Fev, 2022 | 15:42h

Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed – The Guardian

Comentário do autor no Twitter (fio – clique para saber mais)

My new essay @guardian
"Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed"https://t.co/RaBUpET2CZ
Summarizes extensive new evidence that confirmed Prior Covid ("Natural Immunity" or NI) + 1-shot is as protective as 3-shots /1

— Eric Topol (@EricTopol) February 20, 2022

Metanálise mostra que há baixo risco de uma segunda reação alérgica a vacinas de mRNA contra SARS-CoV-2 em pacientes que apresentaram tal reação na primeira dose.

22 Fev, 2022 | 15:40h

Risk of Second Allergic Reaction to SARS-CoV-2 Vaccines: A Systematic Review and Meta-analysis – JAMA Internal Medicine

Comentário no Twitter

Systematic review and meta-analysis of 22 studies and 1366 patients found that there was a low risk of repeat allergic reaction to a second #COVID19 mRNA vaccine dose in people who had immediate allergic reaction with the first dose. https://t.co/NQSXBJwa6r

— JAMA Internal Medicine (@JAMAInternalMed) February 21, 2022

Diretriz prática AAAAI para diagnóstico e tratamento de hipogamaglobulinemia secundária.

22 Fev, 2022 | 14:39h

Practical Guidance for the Diagnosis and Management of Secondary Hypogammaglobulinemia: A Work Group Report of the AAAAI Primary Immunodeficiency and Altered Immune Response Committees – The Journal of Allergy and Clinical Immunology

Visão geral da alergia e da anafilaxia.

22 Fev, 2022 | 14:25h

Overview of Allergy and Anaphylaxis – Emergency Clinics of North America