Alergia e Imunologia
O enigma COVID-19: decifrando a fisiopatologia e os fenótipos de uma nova doença.
7 Mai, 2021 | 10:44h
Comentário no Twitter
We forget that covid-19 is a new disease, never having been seen until late 2019, w/ different features than any prior illness. A truly outstanding review today on its pathophysiology https://t.co/8gx2w8r1xf @LancetRespirMed @osuchm and colleagues pic.twitter.com/WGIfI2nb9B
— Eric Topol (@EricTopol) May 6, 2021
Estudo observacional no Catar: Vacina da Pfizer–BioNTech se mostrou 89,5% eficaz contra a variante B.1.1.7 e 75% eficaz contra a variante B.1.351. A eficácia da vacina contra doença grave, crítica ou fatal com qualquer variante do SARS-CoV-2 foi de 97,4%.
6 Mai, 2021 | 07:45h
Comentário no Twitter
📍GET BOTH DOSES! Great variants & #COVID19 vaccine news—Pfizer/BioNTech vaccine had great efficacy of 89.5% vs #B117 🇬🇧 variant & 75% vs #B1351 🇿🇦 variant for infection—but only with 2 doses. The 1 dose efficacy was just ~29% vs #B117 & ~17% vs #B1351. 🧵https://t.co/SprUfggnmh pic.twitter.com/VDWHiLsQLL
— Eric Feigl-Ding (@DrEricDing) May 6, 2021
Receptores de transplante de órgãos continuam vulneráveis à Covid-19 mesmo depois da segunda dose da vacina.
6 Mai, 2021 | 07:42hEstudo Original: Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients – JAMA
Estudo de coorte mostra resposta imunológica inadequada à vacina de mRNA do SARS-CoV-2 entre receptores de transplante renal.
6 Mai, 2021 | 07:40h
Comentário no Twitter
The studies of mRNA vax in people with transplants are getting bigger: still the same message. Some protection, but not enough. This time, 308 people with kidney transplants in Israel, BNT-Pfizer vaccine https://t.co/Otvt8F11my
— Hilda Bastian, PhD (@hildabast) May 6, 2021
[Preprint] Anticorpos do SARS-Cov-2 permanecem detectáveis 12 meses após a infecção, e sua magnitude está associada com a idade e a gravidade da COVID-19.
5 Mai, 2021 | 09:41hComentário: SARS-CoV-2 antibodies are detectable up to a year after infection, finds study – News Medical
Comentário no Twitter
Ahhh… A year has passed since people with Covid-19 were enrolled in a longitudinal study at 7 US military hospitals. Only a small number checked 12 months later, but signs of immunity still. Immune responses lasting even after milder infection https://t.co/VWsqG8gulT Preprint
— Hilda Bastian, PhD (@hildabast) May 2, 2021
Infecção prévia por SARS-Cov-2 gera resposta às variantes após a primeira dose de vacina
4 Mai, 2021 | 10:10hEstudo Original: Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose – Science
Comentário no Twitter (fio – clique para saber mais)
Just published @ScienceMagazine
"After one dose, individuals with *prior infection* showed enhanced T cell immunity, antibody secreting memory B cell response to spike and neutralizing antibodies effective against B.1.1.7 and B.1.351." 👍https://t.co/7cCVM6iqdP pic.twitter.com/GiC43bjwZZ— Eric Topol (@EricTopol) April 30, 2021
Estudo: Cefazolina é segura para a maioria dos pacientes que desenvolvem reação de hipersensibilidade não mediada por IgE à nafcilina
4 Mai, 2021 | 09:44h
Comentário no Twitter
New case series found 90% tolerated switching to cefazolin out of 80 patients who experienced non-IgE hypersensitivity reactions to nafcillin.https://t.co/YbFeWS4n4k
Our previous metas-analysis https://t.co/sJBjrx4a3r found higher odds of these reactions with nafcillin. pic.twitter.com/SIWcSuPcct— Antibiotic Tweets 🦠 (@khalideljaaly) April 28, 2021
Série de casos de 12 pacientes com trombose do seio venoso cerebral com trombocitopenia após vacinação com Ad26.COV2.S – Todas são mulheres com menos de 60 anos apresentando sintomas entre 6 e 15 dias depois da vacinação
3 Mai, 2021 | 10:50hVer também: Safety Monitoring of the Janssen (Johnson & Johnson) COVID-19 Vaccine — United States, March–April 2021 – Centers for Disease Control and Prevention E Updated Recommendations from the Advisory Committee on Immunization Practices for Use of the Janssen (Johnson & Johnson) COVID-19 Vaccine After Reports of Thrombosis with Thrombocytopenia Syndrome Among Vaccine Recipients — United States, April 2021 – Centers for Disease Control and Prevention
Revisão: Manifestações sistêmicas e órgão-específicas da COVID-19 relacionadas ao sistema imune – mais de 70 diferentes distúrbios sistêmicos e órgão-específicos relacionados ao sistema imune foram relatados
28 Abr, 2021 | 08:31hSystemic and organ-specific immune-related manifestations of COVID-19 – Nature Reviews Rheumatology
O Reino Unido aprovou uma vacina contra o COVID-19 – mas os cientistas ainda têm muitas dúvidas. Uma delas é se as vacinas vão prevenir a transmissão da doença
6 Dez, 2020 | 21:54hThe UK has approved a COVID vaccine — here’s what scientists now want to know – Nature