Acesso livre
Acesso livre

Neurologia

Guia prático de tratamento da síndrome de Dravet com anticonvulsivantes.

28 Abr, 2022 | 11:42h

A Practical Guide to the Treatment of Dravet Syndrome with Anti-Seizure Medication – CNS Drugs


Estudo de coorte | Associação de pressão arterial cumulativa com declínio cognitivo, demência e mortalidade.

27 Abr, 2022 | 15:29h

Association of Cumulative Blood Pressure With Cognitive Decline, Dementia, and Mortality – Journal of the American College of Cardiology

Comentário: Association of Blood Pressure With Cognitive Decline, Dementia, and Mortality – American College of Cardiology


Medicamentos anticolinérgicos e demência: deveríamos nos preocupar?

27 Abr, 2022 | 15:21h

Commonly-prescribed drugs and dementia: should we be worried? – Evidently Cochrane

Revisão original: Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome – Cochrane Library

Editorial: Anticholinergic drugs and dementia: time for transparency in the face of uncertainty – Cochrane Library

Conteúdos relacionados:

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models – Drugs & Aging

Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study – JAMA Internal Medicine

How well do you know your anticholinergic (antimuscarinic) drugs? – Therapeutics Initiative

Anticholinergic drugs and risk of dementia: case-control study – The BMJ

 

Comentário no Twitter

 


Estudo de coorte | Avaliação do escore de probabilidade do plasma amiloide para estimar os achados de tomografia por emissão de pósitrons (PET-CT) entre adultos com comprometimento cognitivo.

27 Abr, 2022 | 15:14h

Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment – JAMA Network Open

 

Comentário no Twitter

 


Estudo de coorte | Associação das experiências adversas na infância com o desenvolvimento de esclerose múltipla.

27 Abr, 2022 | 15:07h

Association of adverse childhood experiences with the development of multiple sclerosis – Journal of Neurology Neurosurgery & Psychiatry

Comunicado de imprensa: Childhood emotional trauma linked to heightened MS risk among women – BMJ Newsroom


Regulador de medicamentos do Reino Unido aconselha pacientes e médicos contra o uso de pregabalina durante a gestação em virtude de um possível risco aumentado de malformações congênitas.

25 Abr, 2022 | 12:40h

Pregabalin (Lyrica): findings of safety study on risks during pregnancy – Medicines and Healthcare products Regulatory Agency

Ver também: Pregabalin and risks in pregnancy – Medicines and Healthcare products Regulatory Agency

Fonte: Avoid prescribing pregabalin during pregnancy if possible, says UK drug regulator – The BMJ ($)

 

Comentário no Twitter

 


Idade sugerida pela retina como um biomarcador preditivo de risco de doença de Parkinson no futuro.

25 Abr, 2022 | 12:19h

Retinal age gap as a predictive biomarker of future risk of Parkinson’s disease – Age and Ageing

Conteúdo relacionado: Retinal age gap as a predictive biomarker for mortality risk – British Journal of Ophthalmology (link para o resumo – $ para o texto completo)


M-A | Associação entre imunoterápicos para o tratamento do câncer e eventos adversos neurológicos.

21 Abr, 2022 | 12:15h

Association of Immune Checkpoint Inhibitors With Neurologic Adverse Events: A Systematic Review and Meta-analysis – JAMA Network Open

Comentário convidado: Neurological Toxic Effects Associated With Treatment With Immune Checkpoint Inhibitors—Are We Really Safer Now? – JAMA Network Open

Conteúdos relacionados:

Autoimmune Encephalitis Related to Cancer Treatment With Immune Checkpoint Inhibitors: Systematic Review – Neurology (link para o resumo – $ para o texto completo)

Neurological complications of immune checkpoint inhibitors: what happens when you ‘take the brakes off’ the immune system – Therapeutic Advances in Neurologic Disorders

 

Comentário no Twitter

 


Estudo de coorte | Associação de queixas subjetivas de memória e focos de hiperintensidade na substância branca com declínio cognitivo entre idosos.

21 Abr, 2022 | 12:03h

Association of Subjective Memory Complaints With White Matter Hyperintensities and Cognitive Decline Among Older Adults in Chicago, Illinois – JAMA Network Open

Comentário: Memory complaints associated with structural brain abnormalities and increased dementia risk – HealthImaging

 

Comentário no Twitter

 


Vídeo | Isso é o que se sabe sobre o impacto da COVID-19 no cérebro.

21 Abr, 2022 | 11:41h

Here’s what we know about COVID-19’s impact on the brain – Science

Conteúdos relacionados:

SARS-CoV-2 is associated with changes in brain structure in UK Biobank – Nature

Nervous system consequences of COVID-19 – Science

The COVID generation: how is the pandemic affecting kids’ brains? – Nature

Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis – Brain, Behavior, and Immunity

Assessment of Cognitive Function in Patients After COVID-19 Infection – JAMA Network Open


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