Acesso livre
Acesso livre

Medicina de Família

Mais dados sugerem que não há benefício cardiovascular na suplementação de ômega 3 – Análise secundária do estudo STRENGHT não mostrou associação entre os níveis atingidos de ácido graxo ômega 3 e desfechos cardiovasculares adversos maiores em pacientes com alto risco cardiovascular.

8 Jun, 2021 | 10:20h

Association Between Achieved ω-3 Fatty Acid Levels and Major Adverse Cardiovascular Outcomes in Patients With High Cardiovascular Risk: A Secondary Analysis of the STRENGTH Trial – JAMA Cardiology

Estudo original: #AHA20 – Randomized trial: High-dose Omega-3 fatty acids did not reduce the risk of cardiac events in patients at high cardiovascular risk

Comentários: Higher blood levels of omega-3 fatty acids from prescription fish oil showed no effect on CV events – American College of Cardiology

Revisão | Conduta em pacientes com tromboembolismo venoso após o período inicial de tratamento.

8 Jun, 2021 | 10:16h

Management of Patients With Venous Thromboembolism After the Initial Treatment Period – The Journal of the American Board of Family Medicine

Estudo mostra atividade reduzida de anticorpos neutralizantes, induzida pela vacina da Pfizer–BioNTech, contra as variantes de preocupação do SARS-CoV-2 B.1.617.2 (Delta) e B.1.351 (Beta).

7 Jun, 2021 | 10:31h

Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2  and B.1.351 (Beta) by BNT162b2 vaccination – The Lancet

Comentário: Pfizer-BioNTech vaccine recipients have lower antibody levels targeting the Delta variant – The Francis Crick Institute

 

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6 meses de vacinas contra COVID: o que 1,7 bilhão de doses ensinaram aos cientistas.

7 Jun, 2021 | 10:30h

Six months of COVID vaccines: what 1.7 billion doses have taught scientists – Nature

Ver também: Coronavirus (COVID-19) Vaccinations – Our World in Data

 

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2 novas metanálises detalham as condições neurológicas e psiquiátricas causadas pela COVID-19.

7 Jun, 2021 | 10:26h

Neurologic, psychiatric conditions common in COVID-19 – CIDRAP

Metanálise 1: Neurology and neuropsychiatry of COVID-19: a systematic review and meta-analysis of the early literature reveals frequent CNS manifestations and key emerging narratives – Journal of Neurology, Neurosurgery & Psychiatry

Metanálise 2: Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings – BMC Infectious Diseases

Relacionado: Large study finds 1 in 3 Covid-19 survivors have subsequent mental health and neurological conditions

Mais dados sobre os efeitos danosos da pandemia de COVID-19 na saúde mental de adolescentes.

7 Jun, 2021 | 10:25h

Depressive symptoms, mental wellbeing, and substance use among adolescents before and during the COVID-19 pandemic in Iceland: a longitudinal, population-based study – The Lancet Psychiatry

Comentários: A lost generation? COVID-19 and adolescent mental health – The Lancet Psychiatry E COVID-19 pandemic has had significant impact on the mental health of adolescents – Columbia University Mailman School of Public Health

 

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Perspectiva | As estatinas poderiam fazer mais do que baixar o colesterol em pacientes com COVID-19? – “Não comece, não pare.”

7 Jun, 2021 | 10:22h

Could Statins Do More Than Lower Cholesterol in Patients With COVID-19? – JAMA

Estudo de coorte: longas horas de trabalho (mais de 55 h/semana) estão relacionadas a risco aumentado de recorrência de eventos coronarianos.

7 Jun, 2021 | 10:10h

Long Working Hours and Risk of Recurrent Coronary Events – Journal of the American College of Cardiology (link para o resumo – $ para o texto completo)

Comentários: Working long hours may increase odds of second heart attack – American College of Cardiology E Recurrent CHD Risk Up With Long Working Hours After First MI – HealthDay E Longer Work Hours After MI Tied to Higher Risk of Recurrent Events – TCTMD

Mais um estudo mostra alta frequência de uso de antibióticos em pacientes hospitalizados com Covid-19 (85,2%), apesar das baixas taxas de confirmação de infecções bacterianas secundárias.

4 Jun, 2021 | 08:27h

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study – The Lancet Microbe

Comentários: Very high use of antibiotics in COVID-19 treatment could be reduced – University of Glasgow E More evidence of frequent antibiotic use noted in COVID patients – CIDRAP E Covid-19: Antimicrobial use was high during first wave despite bacterial co-infections being rare, study finds – The BMJ

Relacionado: Many hospitalized Covid-19 patients are given antibiotics. That’s a problem – STAT

 

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Estudo randomizado: Profilaxia pós-exposição com banlanivimabe reduziu a incidência de Covid-19 entre residentes e equipe de enfermagem de casas de repouso.

4 Jun, 2021 | 08:26h

Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities: A Randomized Clinical Trial – JAMA

Editorial: Bamlanivimab for Prevention of COVID-19

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