Endocrinologia

Diretriz europeia sobre o cuidado da obesidade em pacientes com doenças hepáticas e gastrointestinais.

16 Ago, 2022 | 12:53h

European guideline on obesity care in patients with gastrointestinal and liver diseases – Joint European Society for Clinical Nutrition and Metabolism / United European Gastroenterology guideline – UEG Journal

 

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Estudo de randomização mendeliana de PCSK9 e inibição de HMG-CoA redutase e função cognitiva.

15 Ago, 2022 | 13:39h

Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function – Journal of the American College of Cardiology

Comentários:

Genetic Study Hints at Cognitive Impact of Statins, but Experts Urge Caution – TCTMD

Interpreting the Clinical Implications of Drug-Target Mendelian Randomization Studies – American College of Cardiology

 

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Podcast | Suplementação de vitaminas e minerais: atualização USPSTF.

15 Ago, 2022 | 13:24h

#345 Vitamin and Mineral supplementation: A USPSTF Update with Dr. Michael Barry – The Curbsiders

Conteúdo relacionado: USPSTF Statement: The current evidence is insufficient to recommend vitamins for the prevention of cardiovascular disease or cancer.

 

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Estudo de coorte | Risco de fratura de quadril entre pessoas que consomem carne, que só consomem peixes e em vegetarianos.

12 Ago, 2022 | 18:06h

Risk of hip fracture in meat-eaters, pescatarians, and vegetarians: results from the UK Women’s Cohort Study – BMC Medicine

Comunicado de imprensa: Vegetarian women are at a higher risk of hip fracture – University of Leeds

 

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Estudo randomizado | Tratamento tópico do edema macular diabético com uso de suspensão oftálmica de dexametasona.

12 Ago, 2022 | 17:54h

Topical treatment of diabetic macular edema using dexamethasone ophthalmic suspension: A randomized, double-masked, vehicle-controlled study – Acta Ophthalmologica

Comentário: Topical Dexamethasone Ophthalmic Suspension OCS-01 Effective in DME Treatment – HCP Live

 

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Estudo de coorte | Associação entre agonistas do hormônio liberador de gonadotropina para câncer de próstata e risco de doença cardiovascular e hipertensão em homens diabéticos.

12 Ago, 2022 | 17:53h

Association of Gonadotropin-Releasing Hormone Agonists for Prostate Cancer With Cardiovascular Disease Risk and Hypertension in Men With Diabetes – JAMA Network Open

 

Comentário no Twitter

Study showed men with #T2DM on GnRH for prostate cancer had a 53% higher risk of an increase in CVD risk score than those not on GnRH, suggesting the need to control cardiovascular disease risk factors in men with T2DM receiving GnRH. #OrigInvestigation https://t.co/3cJ10PpQGN

— JAMA Network Open (@JAMANetworkOpen) August 8, 2022

 

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M-A | Efeitos dos substitutos do sal em desfechos clínicos.

12 Ago, 2022 | 17:44h

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart

Comentário: Swapping salt for substitutes reduces risk of stroke and heart conditions – study – The Guardian

Conteúdos relacionados:

Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women – Cochrane Library

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

Comentário da autora no Twitter

Our latest meta-analysis shows consistent effects of salt substitutes on BP across diverse geographies and populations. Protective effects on clinical outcomes are likely to be generalizable to countries worldwide. https://t.co/C273yK6Bek

— Xuejun Yin (@XuejunYin) August 10, 2022

 

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Revisão sistemática | Efeitos da troca de sal por substitutos de sal com baixo sódio na saúde cardiovascular em adultos, crianças e gestantes.

12 Ago, 2022 | 17:42h

Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women – Cochrane Library

Resumo: Does using low-sodium salt substitutes (LSSS) instead of regular salt reduce blood pressure and heart disease risks, and is it safe? – Cochrane Library

Conteúdos relacionados:

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

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Estudo randomizado | Efetividade da restrição do tempo de alimentação para perda de peso, perda de gordura e saúde cardiometabólica em adultos com obesidade.

10 Ago, 2022 | 14:45h

Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss, and Cardiometabolic Health in Adults With Obesity: A Randomized Clinical Trial – JAMA Internal Medicine

Entrevista com a autora: Effectiveness of Early Time-Restricted Eating for Weight Loss and Fat Loss in Adults With Obesity – JAMA

Comentários:

Time-Restricted Eating to Improve Health—A Promising Idea in Need of Stronger Clinical Trial Evidence – JAMA Internal Medicine (gratuito por tempo limitado)

Expert reaction to study looking at early time-restricted eating and weight loss in obese adults – Science Media Centre

Conteúdos relacionados:

Effects of Intermittent Fasting in Human Compared to a Non-intervention Diet and Caloric Restriction: A Meta-Analysis of Randomized Controlled Trials – Frontiers in Nutrition

Time-Restricted Eating: Integrating The What With The When – Advances in Nutrition

Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine (link para o resumo – $ para o texto completo)

Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials – JAMA Network Open

 

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Estudo randomizado | Efeito de um intervenção abrangente de telemedicina vs. telemonitoramento e coordenação de cuidados em pacientes com diabetes tipo 2 de controle persistentemente ruim.

10 Ago, 2022 | 14:26h

Effect of a Comprehensive Telehealth Intervention vs Telemonitoring and Care Coordination in Patients With Persistently Poor Type 2 Diabetes Control: A Randomized Clinical Trial – JAMA Internal Medicine (link para o resumo – $ para o texto completo)

Comentário: Comprehensive telehealth intervention effective for reducing HbA1c in poorly controlled diabetes – Physician’s Weekly

 

Comentário no Twitter

A comprehensive telehealth intervention improved HbA1c in persistently poorly-controlled type 2 diabetes compared to a simpler telehealth intervention; the comprehensive telehealth approach may warrant implementation in systems with appropriate resources. https://t.co/qXnuclyipQ

— JAMA Internal Medicine (@JAMAInternalMed) July 29, 2022

 

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