Emergências e Terapia Intensiva

Série de casos | Vacinas mRNA contra COVID levando a inflamação do SNC.

7 Set, 2021 | 22:06h

COVID-19 mRNA vaccination leading to CNS inflammation: a case series – Journal of Neurology

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Atualização anual em medicina de emergência e terapia intensiva 2021 – Artigos não relacionados a Covid.

7 Set, 2021 | 22:02h

Advanced management of intermediate-high risk pulmonary embolism

Pathophysiology and clinical implications of the veno-arterial PCO₂ gap

To prone or not to prone ARDS patients on ECMO

Management of acute metabolic acidosis in the ICU: sodium bicarbonate and renal replacement therapy

Acute kidney injury in ECMO patients

Monitoring and modifying brain oxygenation in patients at risk of hypoxic ischaemic brain injury after cardiac arrest

Measuring vitamin C in critically ill patients: clinical importance and practical difficulties—Is it time for a surrogate marker?

Still a place for aortic counterpulsation in cardiac surgery and patients with cardiogenic shock?

Ver também: Covid articles

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Estudo de coorte | Marcadores sorológicos de lesão cerebral podem predizer bom desfecho neurológico após parada cardíaca fora do ambiente hospitalar.

7 Set, 2021 | 22:01h

Serum markers of brain injury can predict good neurological outcome after out-of-hospital cardiac arrest – Intensive Care Medicine

 

Comentário no Twitter

Established/novel blood brain injury markers early predict good neuro-outcome/absence of pathological prognostic findings post CA
🧠NSE/S100B may prevent premature WLST
🧠NFL highest predictive capacity
Here visual abstract, full results #FOAMcc @yourICM https://t.co/3klcew33bD pic.twitter.com/1agsFCw6RF

— Intens Care Med (@yourICM) September 4, 2021

 

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Aspectos médicos, éticos e legais dos dilemas de fim de vida na unidade de terapia intensiva.

7 Set, 2021 | 21:58h

Medical, ethical, and legal aspects of end-of-life dilemmas in the intensive care unit – Cleveland Clinic Journal of Medicine

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Podcast | Testes hepáticos.

7 Set, 2021 | 21:52h

#293 The Best of Liver Tests with Dr. Elliot Tapper – The Curbsiders

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Estudo randomizado | Tratamento precoce da COVID-19 com anakinra orientado pelos níveis plasmáticos de receptor de plasminogênio de uroquinase solúvel.

6 Set, 2021 | 16:34h

Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial – Nature Medicine

 

Comentário no Twitter

The SAVE-MORE phase 3 study demonstrates the efficacy of anakinra, an IL-1α/β inhibitor, in patients with COVID-19 and high serum levels of soluble plasminogen activator receptor, according to a @NatureMedicine paper. https://t.co/aM5teLMipK pic.twitter.com/bTVNqbBOcv

— Nature Portfolio (@NaturePortfolio) September 3, 2021

 

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Estudo mostra que as concentrações de troponina cardíaca à apresentação são insuficientes para distinguir infarto do miocárdio tipo 1 de outras causas de lesão miocárdica.

6 Set, 2021 | 16:21h

Cardiac Troponin Thresholds and Kinetics to Differentiate Myocardial Injury and Myocardial Infarction – Circulation

 

Comentário no Twitter

Cardiac troponin release kinetics: levels at presentation cannot distinguish type 1 MI from other causes of injury or infarction. Results now online @CircAHA https://t.co/8cjyl6SGai@HighSTEACS @chapdoc1 @djlmed @DorienKimenai @EdinUniCVS pic.twitter.com/v0RoD532Jx

— Ryan Wereski (@RyanWereski) June 25, 2021

 

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Estudo de coorte diagnóstica | Diferenciação entre causas centrais e periféricas da vertigem aguda em ambiente de emergência com os testes HINTS, STANDING e ABCD2.

6 Set, 2021 | 16:13h

Differentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study – Academic Emergency Medicine (link para o resumo – $ para o texto completo)

Comentário: Can We Detect Central Vertigo on Exam? – Journal Feed

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Revisão | Complicações musculoesqueléticas após doença crítica.

3 Set, 2021 | 12:37h

Musculoskeletal complications following critical illness: A scoping review – Journal of Critical Care

 

Comentário no Twitter

Very pleased that our scoping review on MSK complications following critical illness has been published – first paper from my PhD! @mawilliamsinOx @helendawes2 @matthewjrowland @ouh_therapies @MOReS_OBU #icurehab https://t.co/f6kHDtMzrj pic.twitter.com/bOm3YvLP5U

— Owen Gustafson (@OxfordICUPhysio) August 26, 2021

 

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Estudo randomizado | Baricitinibe reduziu a mortalidade em adultos hospitalizados com COVID-19.

3 Set, 2021 | 11:22h

Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial – The Lancet Respiratory Medicine

Comentários:

Baricitinib: the first immunomodulatory treatment to reduce COVID-19 mortality in a placebo-controlled trial – The Lancet Respiratory Medicine

Rheumatoid Arthritis Drug Combined with Standard of Care May Help Reduce Mortality for Hospitalized COVID-19 Patients – Vanderbilt University Medical Center

 

Comentários no Twitter

NEW—Baricitinib did not improve the composite primary endpoint of progression to NIV,
high-flow O2, IMV, or death; however, it did reduce 28-day all-cause mortality by 38·2% vs placebo (HR 0·57 [95% CI 0·41–0·78])

Read the COV-BARRIER study: https://t.co/QrU6GW0XcQ#ISICEM2021

— The Lancet Respiratory Medicine (@LancetRespirMed) September 1, 2021

(thread – click for more)

1/🧵💥 NEW COVID THERAPY SAVES LIVES

Adding baricitinib to steroids will save 1,000s of hospitalized #COVID pts. Our @LancetRespirMed COV-Barrier study is FREE.

I explain👇why it’s such a great #Pandemic discovery story: a new way to ⬇️ COVID19 deaths.https://t.co/8I5BlwyT2R pic.twitter.com/6KcfQrljqC

— WesElyMD (@WesElyMD) September 1, 2021

 

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