Destaques

Diretriz de especialistas | Estratégias para prevenir infecções de corrente sanguínea por cateter central em hospitais de cuidado agudo.

21 Abr, 2022 | 12:41h

Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

Comentário no Twitter

Prevention of central line-associated bloodstream infections in acute-care hospitals- 2022 updatehttps://t.co/o3AReYvJIu pic.twitter.com/QsgYYezhqj

— K Pavithran (@drkpavithran) April 19, 2022

Artigo sob licença de http://creativecommons.org/licenses/by/4.0/

Estudo observacional sugere que a coprescrição de inibidores da fosfodiesterase tipo 5 (p. e., sildenafila) e nitratos orais não está associada a risco aumentado de desfechos cardiovasculares adversos em homens com doença cardíaca isquêmica.

21 Abr, 2022 | 12:39h

Adverse Events Associated With Coprescription of Phosphodiesterase Type 5 Inhibitors and Oral Organic Nitrates in Male Patients With Ischemic Heart Disease: A Case-Crossover Study – Annals of Internal Medicine

Comentários:

PDE5 inhibitors didn’t increase cardiovascular events in men on nitrates for heart disease – ACP Internist

PDE5 Inhibitors Prescribed for Men on Oral Nitrates for IHD – HealthDay

Estudos destacam o potencial da vacina contra meningite para prevenir a gonorreia.

21 Abr, 2022 | 12:35h

Comentário: Studies highlight meningitis vaccine’s potential against gonorrhea – CIDRAP

Comunicado de imprensa: Threat of untreatable gonorrhoea could be tackled using an existing meningitis vaccine – The Lancet

Estudo 1: Effectiveness of a serogroup B outer membrane vesicle meningococcal vaccine against gonorrhoea: a retrospective observational study – The Lancet Infectious Diseases (link para o resumo – $ para o texto completo)

Estudo 2: Effectiveness and impact of the 4CMenB vaccine against invasive serogroup B meningococcal disease and gonorrhoea in an infant, child, and adolescent programme: an observational cohort and case-control study – The Lancet Infectious Diseases (link para o resumo – $ para o texto completo)

Estudo 3: Public health impact and cost-effectiveness of gonorrhoea vaccination: an integrated transmission-dynamic health-economic modelling analysis – The Lancet Infectious Diseases

Big Techs na atenção à saúde: quem ganha e quem perde com Alphabet, Amazon, Apple e Microsoft mirando o nicho de atenção à saúde.

21 Abr, 2022 | 12:32h

BIG TECH IN HEALTHCARE: Here’s who wins and loses as Alphabet, Amazon, Apple, and Microsoft target niche sectors of healthcare – Insider Intelligence

Covid não revelou todos os seus segredos. Aqui estão 6 mistérios que os especialistas esperam desvendar.

21 Abr, 2022 | 12:30h

Covid hasn’t given up all its secrets. Here are 6 mysteries experts hope to unravel – STAT

Estudo controlado não randomizado: posição prona em paciente não intubado (média de 4,2 horas/dia) pode não ser benéfica para adultos internados com Covid-19.

21 Abr, 2022 | 12:29h

Assessment of Awake Prone Positioning in Hospitalized Adults With COVID-19: A Nonrandomized Controlled Trial – JAMA Internal Medicine

Comentários:

Prone Positioning for Nonintubated Patients With COVID-19—Potential Dangers of Extrapolation and Intermediate Outcome Variables – JAMA Internal Medicine

Study suggests worse outcomes for awake COVID patients in prone position – CIDRAP

Putting Hospitalized COVID Patients on Their Belly May Not Be a Good Idea After All – HealthDay

Conteúdos relacionados:

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE) – The BMJ

RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv

Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial – The Lancet Respiratory Medicine

Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial – Critical Care

Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis – Critical Care Medicine

Comentário no Twitter (fio – clique para saber mais)

Important negative study: non randomized trial finds no clinical benefit to awake proning vs usual care in COVID

No difference in rates of intubation, length of stay, or 28 day mortality

Medicine is humbling. This emphasizes the importance of trials
📄https://t.co/ksh9Ic9XBL
1/ pic.twitter.com/sjHHv4WQs8

— Nick Mark MD (@nickmmark) April 18, 2022

FDA alerta para os riscos associados aos testes de rastreamento pré-natal não invasivos – interpretação inadequada dos resultados pode levar a potenciais decisões médicas impróprias.

21 Abr, 2022 | 12:27h

FDA Warns of Risks Associated with Non-Invasive Prenatal Screening Tests – U.S. Food & Drug Administration

Ver também: Genetic Non-Invasive Prenatal Screening Tests May Have False Results: FDA Safety Communication – U.S. Food & Drug Administration

Diretriz AAOS | Prevenção de infecções em sítio cirúrgico após trauma extenso em extremidades.

21 Abr, 2022 | 11:46h

Prevention of Surgical Site Infections After Major Extremity Trauma: Evidence-Based Clinical Practice Guideline – American Academy of Orthopaedic Surgeons

Revisão de evidência: Prevention of Surgical Site Infection After Extremity Trauma (2022)

Opinião | Câncer de próstata de baixo grau (escore 6 de Gleason): hora de parar de chamar isso de câncer.

21 Abr, 2022 | 11:44h

Low-Grade Prostate Cancer: Time to Stop Calling It Cancer – Journal of Clinical Oncology

Comentário: Doctors suggest new names for low-grade prostate cancer – Associated Press

Liberadas para estudo clínico as vacinas candidatas da Sinopharm e Sinovac específicas para variante Ômicron da COVID.

21 Abr, 2022 | 11:42h

Omicron-specific Sinopharm, Sinovac COVID vaccine candidates cleared for clinical trial – Reuters