Destaques
CDC alerta sobre novos casos de hepatite de origem desconhecida.
25 Abr, 2022 | 12:44hComentários:
CDC issues health advisory about acute hepatitis in children – CNN
CDC Issues Alert for Hepatitis in Children With Adenovirus Infection – WebMD
Conteúdos relacionados:
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Seguimento de 1 ano de estudo randomizado | Em pacientes em UTI com hipoxemia grave, não houve diferença na mortalidade de longo prazo e na qualidade de vida relacionada à saúde com alvos de oxigenação mais baixos vs. mais altos.
25 Abr, 2022 | 12:42hEstudo original: Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine
Comentário no Twitter
Lower (8 kPa) vs higher oxygenation (12 kPa) targets: no longterm survival benefit nor HRQoL improvement at 1y in #ICU pts with severe hypoxaemia (HOT-ICU trial cohort). Substantial impairments in several EQ-5D-5L dimensions in survivors in both groups.
🖇️ https://t.co/P48Cd5sIWK pic.twitter.com/JBFEIqDdcB— Intensive Care Medicine (@yourICM) April 20, 2022
Regulador de medicamentos do Reino Unido aconselha pacientes e médicos contra o uso de pregabalina durante a gestação em virtude de um possível risco aumentado de malformações congênitas.
25 Abr, 2022 | 12:40hVer também: Pregabalin and risks in pregnancy – Medicines and Healthcare products Regulatory Agency
Fonte: Avoid prescribing pregabalin during pregnancy if possible, says UK drug regulator – The BMJ ($)
Comentário no Twitter
The Medicines and Healthcare Products Regulatory Agency (@MHRAgovuk) has strengthened its warning about avoiding pregabalin during pregnancy after new data showed an increased risk of major congenital malformations associated with the drug https://t.co/ghGvqCqA0C
— The BMJ (@bmj_latest) April 22, 2022
Análise longitudinal de dados de 15 países | Rigor das políticas e saúde mental durante a pandemia de COVID-19.
25 Abr, 2022 | 12:39hComunicado de imprensa: Stricter COVID-19 measures associated with negative mental health effects and lower opinion of government’s pandemic response, new research suggests – The Lancet
Estudo randomizado | Restrição calórica combinada com jejum intermitente (alimentação das 8 às 16 horas) não reduziu de maneira significativa a perda de peso em comparação à restrição calórica isolada em 12 meses (diferença – 1,8 kg; 95% IC, − 4 a 0,4; P = 0,11).
25 Abr, 2022 | 12:31hCalorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comentário: Time-Restricted Eating No Better Than Cutting Calories for Obesity – HealthDay
Conteúdo relacionado: Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials – JAMA Network Open
Comentário no Twitter
As compared with calorie restriction, time-restricted eating does not produce additional benefits with regard to reduction of body weight, body fat, and metabolic risk factors. https://t.co/Ygx4zbC6QP pic.twitter.com/TGE5Pva3yS
— NEJM (@NEJM) April 20, 2022
Estudo randomizado | AZD7442 (tixagevimabe–cilgavimabe) intramuscular para prevenir Covid-19.
25 Abr, 2022 | 12:29h
Comentário no Twitter
AZD7442 (tixagevimab/cilgavimab) found to have about 76% efficacy in preventing symptomatic Covid-19 infection. https://t.co/8tmvz3xI4I pic.twitter.com/fOegZjBRA6
— NEJM (@NEJM) April 20, 2022
[Comunicado de imprensa – ainda não publicado] Novas diretrizes da OMS recomendam um tratamento mais simples e seguro para doença criptocócica em pessoas que vivem com HIV.
25 Abr, 2022 | 12:28hEstudo relacionado: Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Vacinação contra SARS-CoV-2 e miocardite em um estudo de coorte nórdico com 23 milhões de residentes.
25 Abr, 2022 | 12:26hEditorial: Communicating the Benefits of Vaccination in Light of Potential Risks
Estudo de coorte | Infecção por COVID-19 garantiu aos pacientes uma proteção forte e duradoura contra reinfecção.
25 Abr, 2022 | 12:25hComunicado de imprensa: COVID-19 infection granted patients strong and long-lasting protection from reinfection – Providence Health & Services
Estudo original: Rates of COVID-19 Among Unvaccinated Adults With Prior COVID-19 – JAMA Network Open
Comentário: COVID-19 infection may offer similar immunity as vaccination – CIDRAP
Comentário no Twitter
This US cohort study found that unvaccinated individuals with prior symptomatic #COVID19 had 85% lower risk against recurrent COVID-19 compared to unvaccinated individuals without prior infection, for up to 9 months, through November, 2021. https://t.co/1qHCFmGqXG
— JAMA Network Open (@JAMANetworkOpen) April 20, 2022
Diretriz preliminar USPSTF | Mulheres na pós-menopausa não deveriam usar hormonioterapia para evitar problemas crônicos de saúde.
21 Abr, 2022 | 12:44hDiretriz preliminar de recomendação: Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons – U.S. Preventive Services Task Force
Comunicado de imprensa: Task Force Issues Draft Recommendation Statement on Hormone Therapy for Preventing Chronic Conditions in Postmenopausal People – U.S. Preventive Services Task Force
Comentário: USPSTF Advises Against Hormone Therapy to Prevent Chronic Conditions – HealthDay