Destaques

Estudo de coorte | Trajetória de 1 ano das alterações cognitivas em sobreviventes idosos da COVID-19 em Wuhan, na China.

9 Mar, 2022 | 13:46h

One-Year Trajectory of Cognitive Changes in Older Survivors of COVID-19 in Wuhan, China: A Longitudinal Cohort Study – JAMA Neurology

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OMS afirma que doses de reforço da vacina contra COVID são necessárias, revertendo recomendação anterior.

9 Mar, 2022 | 13:45h

WHO says COVID boosters needed, reversing previous call – Associated Press

 

Comentário no Twitter

Who needs a booster? The @WHO reverses its position and supports "urgent and broad" 3-shot vaccination https://t.co/y5pyY9bJr7 @AP The evidence has supported that move for several months.
"Fully vaccinated" = 3-shots
(or confirmed infection-acquired immunity + 1 shot)

— Eric Topol (@EricTopol) March 8, 2022

 

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Segurança das vacinas de mRNA administradas durante os primeiros 6 meses no programa de vacinação contra COVID-19 dos EUA.

9 Mar, 2022 | 13:44h

Safety of mRNA vaccines administered during the initial 6 months of the US COVID-19 vaccination programme: an observational study of reports to the Vaccine Adverse Event Reporting System and v-safe – The Lancet Infectious Diseases

Comentários:

Large US study confirms most mRNA COVID-19 vaccine side effects are mild and temporary – Lancet

Covid vaccines not linked to deaths, major US study finds – BBC

Most mRNA COVID vaccine adverse events mild, transient – CIDRAP

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Diretriz Científica AHA | Interações medicamentosas na cárdio-oncologia.

8 Mar, 2022 | 18:41h

Cardio-Oncology Drug Interactions: A Scientific Statement From the American Heart Association – Circulation

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Estudo randomizado | Azitromicina não é efetiva na prevenção de sibilo recorrente após bronquiolite grave causada por vírus sincicial respiratório.

8 Mar, 2022 | 18:40h

Azithromycin to Prevent Recurrent Wheeze Following Severe Respiratory Syncytial Virus Bronchiolitis – NEJM Evidence

Comentários:

Study finds azithromycin use during RSV not useful in preventing recurrent wheezing, may cause harm – Vanderbilt University Medical Center

Antibiotic doesn’t prevent future wheezing in babies hospitalized with RSV – Washington University in St. Louis

 

Comentário no Twitter

This RCT tested oral azithromycin vs placebo to reduce recurrent wheeze (RW) in 1-18-month-olds hospitalized with acute severe RSV bronchiolitis. Azithromycin did not reduce occurrence of RW and may increase risk of RW in some groups. #AAAAI22 #Asthma #EBM https://t.co/jYcBuiQ8aY pic.twitter.com/u65NbQaIlX

— NEJM Evidence (@NEJMEvidence) February 28, 2022

 

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Fazer mais pode ser pior: 10 erros comuns em UTI.

8 Mar, 2022 | 18:38h

Doing More Can Be Worse: Ten Common Errors in the ICU – ICU Management & Practice

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Estudo randomizado | Rastreamento para fibrilação atrial em idosos por meio de ECG de derivação única não aumentou as taxas de detecção em 1 ano.

8 Mar, 2022 | 18:38h

Screening for Atrial Fibrillation in Older Adults at Primary Care Visits: the VITAL-AF Randomized Controlled Trial – Circulation (link to abstract – $ for full-text)

Conteúdos relacionados:

USPSTF Recommendation Statement: Still not enough evidence to recommend atrial fibrillation screening.

#ESCCongress – RCT: In individuals at risk for stroke, screening for atrial fibrillation using loop recorder resulted in a three-times increase in atrial fibrillation detection and anticoagulation initiation but did not reduce the risk of stroke or systemic arterial embolism.

#ESCCongress – RCT: Small benefit from systematic screening for atrial fibrillation in older adults – After a median follow-up of 6.9 y there were fewer events (stroke, embolism, bleeding, and death) in the intervention group (31·9%) vs. control group (33·0%).

Clinical Review: Screening and management of atrial fibrillation in primary care

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Estudo mostra que o número de infecções por Covid-19 não identificadas por testes de fluxo lateral é “substancial o bastante para ter importância clínica.”

8 Mar, 2022 | 18:36h

Comunicado de imprensa: Number of covid-19 infections missed by lateral flow tests “substantial enough to be of clinical importance,” warn experts – BMJ

Estudo original: SARS-CoV-2 antigen lateral flow tests for detecting infectious people: linked data analysis – The BMJ

Comentários:

Lateral flow tests may be missing ‘substantial’ number of COVID-19 infections – Imperial College London

Self-testing for asymptomatic non-contacts using rapid antigen tests—is this leading to a cost effective reduction in infection transmission? – The BMJ

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Dois imunologistas explicam quanto tempo dura a imunidade protetora contra COVID-19 após infecção ou vacinação.

8 Mar, 2022 | 18:34h

How long does protective immunity against COVID-19 last after infection or vaccination? Two immunologists explain – The Conversation

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A próxima variante: 3 questões centrais sobre o que vem depois da Ômicron.

8 Mar, 2022 | 18:33h

The next variant: three key questions about what’s after Omicron – Nature

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